Similarly, the number of Tc17 cells (RORγt+ in CD8+), and activated and proliferating Tc17 (RORγt+Ki67+CD44+ in CD8+), which are emerging as an important pro-inflammatory cell types that induce cancer cell death, were also >10-fold significantly higher than the controls in the tumours (Fig. 6e, f). Here, CD44 is linked to neoplasm.