IGFBP7 expression was upregulated in breast cancer, glioblastoma, and esophageal adenocarcinoma and downregulated in colorectal cancer, colon cancer, glioma, hepatocellular carcinoma, high-grade serous ovarian carcinoma, pancreatic cancer, and thyroid carcinoma. Here, IGFBP7 is linked to colonic neoplasm.