We observed decreased levels of SPX in FF from the obese group at 0.49 ± 0.02 ng/mL, PCOS normal weight at 0.42 ± 0.02 ng/mL, and obese PCOS at 0.52 ± 0.02 ng/mL compared to 0.88 ± 0.07 ng/mL in normal weight women (Figure 1C, P < 0.05). The gene discussed is SPX; the disease is polycystic ovary syndrome.