This may either be sporadic due to CpG island hypermethylation of MLH1 promoter region (CIMP) or inherited as in Lynch syndrome (2–3%) [4] due to germline mutations in mismatch repair genes (MLH1, MSH2, MSH6, PMS2, MLH3, MSH3, PMS1, EPCAM). Here, MLH1 is linked to Lynch syndrome.