FGF21 and prediabetes syndrome: In addition, an increasing trend of FGF-21 in the normoglycemia group (146.6 [95.5, 247.3] pg/mL), prediabetes group (160.6 [104.3, 246.3] pg/mL), and diabetes group (257.8 [159.8, 339.2] pg/mL) was detected in this study (P for trend < 0.001).