However, since we observed circulating miR-142−/−BCR-ABL blasts, immunophenotypically consistent with LSKs and GMPs, and previous reports suggested that LSCs may also reside in the GMP fraction of CML models38, we conducted transplant experiments to identify which of these fractions from miR-142−/−BCR-ABL or miR-142+/+BCR-ABL mice were more LSC-enriched. Here, ABL1 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.