In contrast, both miR-142+/−BCR-ABL and miR-142−/−BCR-ABL mice had 100% penetrance of a BC-like phenotype characterized by higher white blood cell (WBC) counts (Fig. 1d; Supplementary Fig. 2a), circulating blasts (Fig. 1e, Supplementary Fig. 2c, d), anemia and thrombocytopenia (Supplementary Fig. 2e) as compared with the miR-142+/+BCR-ABL mice. Here, ABL1 is linked to anemia.