Using a chromatin immunoprecipitation assay, we also showed that NRF2 was enriched on the CPT1B promoter and associated with higher CPT1B mRNA expression level both in the miR-142−/−BCR-ABL LSKs and human BC CD34+CD38− cells as compared with their respective mouse and human CP CML controls (Fig. 5c; Supplementary Fig. 7f). Here, CPT1B is linked to breast cancer.