FOXP3 and laryngotracheoesophageal cleft: and characterised by CD45RA and FoxP3 (Fig. S1d), LC patients exhibited an increase in CD161+ Tregs (p < 0.0001; Fig. 1d), a marker preferentially expressed by FoxP3lo Tregs (CD45RA+FoxP3lo and CD45RA−FoxP3lo; Fig. S1e).46, 47, 48