The study uncovered that BXD prevented colon cancer from progressing malignantly, which may be due to various compounds (berberine, quercetin, baicalein, etc.), multiple targets (Bcl-2, Bax, IL-6, TNF-α, CASP3, etc.), and multiple pathways (human cytomegalovirus infection, AGE-RAGE signaling pathway in diabetic complications, etc.). The gene discussed is RENBP; the disease is malignant colon neoplasm.