CD4 and neoplasm: Second, by assessing paracancer immune cell infiltration, we were able to determine that the low-risk group had a significantly higher abundance of memory B-lymphocytes, plasma cells, regulatory T cells, monocytes, resting dendritic cells, and resting mast cells than the high-risk group, while the tumor tissue from the high-risk samples contained significantly more infiltrated activated CD4 memory T cells, resting natural killer cells, M0 macrophages, and activated mast cells (Fig. 7B).