Then, we infected CCF-STTG1 cells with ZIKV, and the results indicate that the knockdown of LGP2 enhances ZIKV RNA replication at 24 and 36 hours post-infection (hpi) (Fig 1C), and enhances ZIKV titer at 24 and 36 hpi (Fig 1D). The gene discussed is DHX58; the disease is infection.