In addition, Bifidobacterium and norank_f__Erysipelotrichaceae negatively correlated with tight junction protein ZO-1 and occludin expression in colon and ileum but positively correlated with serum cTnI and CK levels, the myocardial infarct area, HE score, apoptosis rate, inflammatory factors (IL-1β, IL-6 and TNF-α) in colon and ileum, and serum LPS and Zonulin concentration (Fig 8). Here, HP is linked to hereditary elliptocytosis.