Although the sensitivity varies between studies from 24 to 100%, detection of MNDA expression is also a useful tool since it is one of the few “positive” markers in SMZL (and in other MZL) [7, 9–11] that can be useful in the distinction from follicular lymphoma (almost always negative) and lymphoplasmocytic lymphoma (LPL, frequently negative) [12]. The gene discussed is LPL; the disease is marginal zone lymphoma.