Notably, in lung cancer, we observed higher level of UBA3 expression in LUAD (n = 515) than adjacent normal tissues (n = 59) (P = 0.0237, Fig. 1A); however, no significant differences were observed between LUSC (n = 501) and the control normal tissues (n = 51) (P = 0.1087, Fig. 1A). The gene discussed is UBA3; the disease is lung cancer.