ALB and infection: Hepatologists appear to have a low threshold for prescribing antibiotics to patients with cirrhosis even in the absence of a firm diagnosis of active infection, with a secondary analysis from the multicenter ATTIRE (albumin to treat infection in patients with chronic liver failure) randomized controlled trial of patients hospitalized with decompensated liver disease demonstrating that 49.8% of patients who were prescribed antibiotics on admission did not have a diagnosis of infection.1,2