PLCG1 and infection: BoHV-1 productive infection in Madin-Darby bovine kidney (MDBK) cells leads to sustained activation of PLC-γ1, as demonstrated by increased protein levels of phosphorylated-PLC-γ1 at Ser1248 [p-PLC-γ1(S1248)] (Fig. 1), which is in line with our previous report (14).