SMARCA2 and neoplasm: To objectively find all ICB-induced changes specific to BrM, we adjusted for basal level difference between the 2 tumor types by calculating the DEG (in log2 fold) between ICB-naive (log2FCBrM-rGBM) and ICB-treated BrM and rGBM samples (log2FCBrM.ICB-rGBM.ICB).