At this point in time, we observed upregulation of tubule cell Kdm6a levels, like that previously observed in the glomeruli, podocytes, mesangial cells or tubule cells of mice and humans with diabetes or focal segmental glomerulosclerosis (Chen et al., 2019; Lin et al., 2019; Majumder et al., 2018). The gene discussed is KDM6A; the disease is focal segmental glomerulosclerosis.