TSHR and Graves disease: Graves’ orbitopathy (GO) is an autoimmune disorder that threatens the sight of patients with Graves’ disease.73 Thyrotropin receptor autoantibody (TRAb) is recommended by the Thyroid Association guidelines as a marker for Graves’ disease and for GO management.74 In patients with GO, who had high levels of TRAb, the abundance of the family Prevotellaceae, and P. copri species, in particular, in the gut microbial community was correlated with TRAb levels.