They have the ability to accelerate the development of colorectal tumors (Okumura et al., 2021), stimulate the recruitment of tumor-infiltrating myeloid cells, and promote the development of colorectal tumorigenesis through the activation of the PI3K/AKT23 and JAK/STAT324 signaling pathways, as well as inhibition of apoptosis through the inhibition of mitochondrial membrane permeability and cytochrome-c release (Yao et al., 2010; Nakayama et al., 2015; Wang et al., 2021). Here, CYCS is linked to neoplasm.