CD38 and relapsing-remitting multiple sclerosis: It can significantly reduce Bregs (CD24+CD38high), mature B cells (CD24+CD38low) and, to a lesser extent, memory B cells (CD24+CD38-) in the peripheral blood of patients with RRMS.61 Yilmazet al. reported a reduction of PC in the peripheral blood of patients with RRMS, who were treated with teriflunomide.62