NOS3 and atherosclerosis: Since atherosclerosis origin and progression depend on inflammatory leukocyte recruiting and macrophage activation, banana peel compounds were found to inhibit both the expression of NFkB and chemoattractant and adhesion molecules; they were also associated with enhanced production of endothelial isoform of nitric oxide synthase (e-NOS), favoring vasodilation (Ahmad et al., 2019).