Thus, similar to SARS-CoV infection, SARS-CoV-2 infection increases the secretion of interleukin 1 beta (IL-1β), interferon-c (IFN-c), human interferon-inducible protein 10 (IP-10), monocyte chemoattractant protein-1 (MCP-1), IL-4, and IL-10. Here, IL1B is linked to severe acute respiratory syndrome.