Similarly other recent studies also reported elevated levels of urinary albumin levels in type 2 diabetes mellitus with micro albuminuria when compared to normo andhealthy individuals, along with that they reported urinary albuminuria is not an a specific and sensitive biomarker for early detection of nephropathy in type 2 diabetes mellitus due longer duration to excrete due to size of the albumin is more, it is elevatedin other conditions like obesity, hypertension, other systemic and metabolic disorders [20]. The gene discussed is ALB; the disease is obesity due to melanocortin 4 receptor deficiency.