Currently, several prediction models were established for the occurrence of HCA during pregnancy using some laboratory indexes including the neutrophil–lymphocyte ratio, maternal C-reactive protein (CRP), intercellular adhesion molecule-1 (ICAM-1), interleukin 6 (IL-6), interleukin 8 (IL-8), and matrix metalloproteinase 8 and 9 (MMP-8 and MMP-9) (12–15). This evidence concerns the gene IL6 and hepatocellular adenoma.