ANA ≥ 1/80, followed by anti-Ro, was the most frequent autoantibody in patients with UIP pattern and NSIP pattern at HRCT, ANA ≥ 1/80 and anti-Ro were the most frequent autoantibodies in patients with arthritis, while isolated positivity of anti-Ro was frequent in patients with Raynaud phenomenon. The gene discussed is CALR; the disease is arthritic joint disease.