Leukopenia, thrombocytopenia, erythrocytopenia, and bone marrow cell depletion are caused by radiation therapy associated with hemorrhage, which increases the production of IL-1, IL-6, and IL-17A in the IL-17 signaling pathway and increases BMS (Kiang et al., 2015). The gene discussed is IL1B; the disease is Decreased total leukocyte count.