To examine the putative beneficial effects of an EVOO-enriched diet supplementation on insulin resistance markers in GDM women, TG/HDL cholesterol ratio and FABP4 levels were evaluated in plasma samples in a cohort of control (n = 15), GDM (n = 15), and GDM patients who received the dietary EVOO supplementation from enrollment to term (n = 15). The gene discussed is FABP4; the disease is gestational diabetes.