Various epithelial markers including epithelial cell adhesion molecule (EpCAM), cadherin 1 (Cdh1), keratin (Krt) 5/14, desmoglein 2 (Dsg2), and epithelial splicing regulatory protein 1/2 (Esrp1/2) have been adopted to depict the EMT states of cancers.30 This evidence concerns the gene DSG2 and cancer.