ANK3 and Behcet disease: Interestingly, ANK3 exon 1b isoform is expressed mainly in GABAergic interneurons and knock‐out mice deficient for exon 1b show reduced NaV channels at the AIS of parvalbumin‐positive interneurons (which have increased firing thresholds and diminished AP dynamic range), behavior dysfunctions modeling BD, epilepsy, and sudden death (Lopez et al., 2017).