CASP3 and colorectal cancer: Phenolics from medicinal plant extracts such as p-coumaric, protocatechuic, and caffeic acids, some of which were reported for CA and PR, are apoptotic inductors elevating caspase-3 levels, reducing membrane potential, and inducing morphological changes in breast, prostate, lung, cervical, fibrosarcoma, and colorectal cancer cells [40,41].