Quercetin ameliorated neuro-inflammation in mice by modulating the NLRP3 pathway in NOD-like receptor signaling, which was demonstrated by reducing IL-1β and IL-18 levels.[52] Naringin inhibits NF-κB activation and the NOD-like receptor family in NLRP3 inflammasomes.[53] The key targets and pathways screened in the current study are potential targets and pathways for the therapeutic efficacy of uveitis. This evidence concerns the gene IL18 and uveitis.