ATP7A, a copper efflux transporter, is critical for the delivery of copper to physiological processes, whereas Menkes and Wilson diseases are accompanied by dysregulation of ATP7A function.[16] In our study, we found that ATP7A expression was higher in HCC tissues than in adjacent normal tissues, and it was a risk factor for HCC prognosis. The gene discussed is ATP7A; the disease is hepatocellular carcinoma.