The function of NRAV is related to immune checkpoints,[30] ferroptosis,[31] and activation of Wnt/β-catenin signaling through regulation of the miR-199a-3p/CISD2 axis,[32] implying that NRAV may participate not only in copoptosis but also in activating other signaling pathways to perform its function in the tumorigenesis of HCC. Here, NRAV is linked to hepatocellular carcinoma.