CRYBG2 and cancer: According to our immunohistochemical results and chi-square test, we found that AIM1L was highly expressed in the cytoplasm of esophageal normal squamous epithelial tissues and cancer tissues (P > .05), whereas in the nucleus, AIM1L was highly expressed in esophageal normal squamous epithelial tissues (29/36) and cancer tissues (18/36), with significant difference (P < .05 Fig. 8).