Thus, included variables were age, sex, BMI, abdominal obesity, hypertension, diabetes, smoking status, sedentary lifestyle, dietary intake of fiber and β-carotene, levels of HDL cholesterol, triglycerides, CRP, IL-6 and IL-18, granulocyte counts and proportions of naïve CD4+, naïve Treg cells and naïve CD8+ T cells. The gene discussed is IL18; the disease is diabetes mellitus.