In another study, orally administered ginger-derived exosome-like nanoparticles exhibit preferential uptake by Lactobacillaceae in intestinal microbiota, and specifically target specific genes of Lactobacillus rhamnosus (LGG), contributing to the alteration in the composition of gut microbiota and the increased levels of IL-22, thereby restoring intestinal barrier function and mitigating mice colitis [23]. This evidence concerns the gene IL22 and colitis.