AKT1 and Kaposi's sarcoma: Additionally, MIP was detected in KS samples which can be indicative of dysregulated signaling pathways such as the phosphoinositide 3-kinase-protein kinase B (PI3K-AKT) pathway and can directly affect the activity of lipogenic enzymes and thus the lipid composition, particularly phosphatidylinositol (PI) [33, 34].