We further developed a CIP signature (CXCL9/10/11/13, CXCR3/6, FASLG, and IFNG), and found that the CIP signature expressed a high level in CIP+ tissue samples than CIP− tissue samples (Fig. 8H), and achieved a high diagnostic power to distinguish CIP+ tissue sample from CIP− tissue samples (Fig. 8I). This evidence concerns the gene CXCL9 and hereditary sensory and autonomic neuropathy.