Data presented in Fig. 3 showed significantly higher serum levels of GnRH, LH and FSH in the AD group (80.9 ± 4.2 pg/ml, 7.8 ± 0.5 mIU/ml, 11.1 ± 0.4 ng/ml, respectively) as compared to the control group (55.4 ± 5.2 pg/ml, 5.2 ± 0.6 mIU/ml, 9 ± 0.3 ng/ml, respectively), p < 0.001 for all. This evidence concerns the gene BRD2 and Alzheimer disease.