TP53 and pulmonary fibrosis: Similar to the phenotype of p53-cKO mice (Fig. 4), Tgfbr2-cKO mice showed resistance to BLM-induced lung fibrosis with less body weight loss (Supplementary Fig. 6b), less deposition of collagen, smaller fibrotic lesion area on day 21, and fewer myofibroblasts on day 7 (Fig. 7c, d), which was consistent with the results of the ex vivo lung-lobe culture (Supplementary Fig. 6c) and a previous report using Nkx2.1-cre driver34.