The multivariate linear regression analysis revealed independent positive associations of ECW/TBW ratio with male sex (β = 0.189), age (β = 0.215), history of diabetes (β = 0.142), Log CRP (β = 0.133), CTR (β = 0.213), and simple PEW score (β = 0.256) (Table 2). The gene discussed is CRP; the disease is diabetes mellitus.