LGALS3 and systemic sclerosis: To investigate a potential association between the Gal-3 network and SSc, we first established a list of known Gal-3 partners through bioinformatic queries within the Ingenuity Pathway Analysis (IPA) and GPS-Prot databases and established a non-redundant list of 307 interactants (Supplementary Data 1, column A) of which 248 could be retrieved from whole-blood RNA sequencing (RNAseq) data from the PRECISESADS SSc cohort, after exclusion of 59 genes absent from the dataset (Supplementary Data 1, column C).