For example, MYBPC3 c.1544A>G (p.Asn515Ser) (GenBank: NM_000256.3) was identified 5/492 times in AFR affected individuals (AF = 0.005) and 33/10,655 times in AFR population participants (AF = 0.0016; penetrance of 0.6% [0.2%–1.5%]) compared to 1/9,692 times in EUR affected individuals (AF = 0.00005) and not observed in 211,532 EUR population participants. Here, MYBPC3 is linked to atrial fibrillation.