Given the clinical relevance of PLCγ expression in RCC, the potential disease impact of differentially expressed genes (DEGs) with a log2 fold change of more than 1.0 or less than –1.0 in the PLCG1-high and -low subgroups in the KIRC cohort (Supplemental Data File 1) was assessed by examining enrichment of gene ontology biological processes (GOBPs). Here, PLCG1 is linked to renal cell carcinoma.