The therapeutic effects of the iMSC-derived exosomes included a reduction in histopathological signatures of liver fibrosis (hepatocyte necrosis and sinusoidal congestion), reduction in serum aspartate aminotransferase (AST) and alanine aminotransferase (ALT) and promoted hepatocyte proliferation in a dose-dependent manner [92]. This evidence concerns the gene GPT and Hepatic fibrosis.