MYC and B-cell non-Hodgkin lymphoma: Moreover, mice deficient in Trp73, presumably p73α, were prone to spontaneous tumors, such as lymphoma (Figure 4E), consistent with previous observations that loss of Trp73 promotes Myc-induced B-cell lymphomas or mutant p53-mediated T-cell lymphomas (Zhang et al., 2019; Nemajerova et al., 2010).