We and others have shown that ectopic expression of TAp73α and TAp73γ can inhibit cell growth albeit to a much less extent compared to p53 or TAp73β (Liu and Chen, 2005; Ueda et al., 1999; Nozell et al., 2003; Chi et al., 1999), suggesting that TAp73α and TAp73γ have a role in tumor suppression. This evidence concerns the gene TP53 and neoplasm.