Mouse (M. musculus) — 25 mg/kg body weight per day results in weight-loss of 5–7%, decreased cholesterol and blood-insulin (at 9 & 15, and after 12 months of treatment, respectively), improved rotartod performances (after 12 and 18 months of treatments!) [69].In addition, kaempferol (30 mg per kg bodyWeight per day, for 30 days) decrease tumor volume and mass by 65.93% and 49.25%, respectively, in a mice model of human liver cancer xenograft [70]. Here, INS is linked to liver cancer.