TRPM6 and chronic obstructive pulmonary disease: Ultimately, expression levels of ABR, TRPM6, and RORC were detected in the blood of patients with COPD in the clinical stages of disease (data derived from GEO dataset GSE54837), and based on the severity of disease, mRNA expression levels of ABR and TRPM6 were increased and that of RORC was decreased (Figure 9E).