We also assessed the longitudinal associations between the GGT/HDL-C ratio and the risk of CVD incidence after additional adjustment for lifestyle factors, including alcohol intake and major metabolic parameters, such as mean arterial blood pressure, fasting plasma glucose, total cholesterol, alanine aminotransferase, C-reactive protein, hypertension, and diabetes mellitus (models 2 and 3). This evidence concerns the gene GPT and hypertensive disorder.