However, our findings are consistent with other mouse models of ASD including SHANK3 mutants (associated with Phelan-McDermid syndrome) and Fmr1 mutants (associated with Fragile-X Syndrome), which also show no impairment in PPI (Jaramillo et al., 2016; Schaefer et al., 2017). The gene discussed is SHANK3; the disease is fragile X syndrome.