SSM: Superficial spreading melanoma; ALM: Acral lentiginous melanoma; NM: Nodular melanoma; LMM: Lentigo maligna melanoma; TILs: Tumor-infiltrating lymphocytes; BRAF: v-raf murine sarcoma viral oncogene homolog B. The gene discussed is BRAF; the disease is nodular malignant melanoma.